Applied Micro Circuits Corporation (also known as AppliedMicro or AMCC or APM) is a fabless semiconductor company designing network and embedded Power Architecture (including a Power Architecture license), and server processor ARM (including an ARMv8-A license), optical transport and storage products.

In 2004, AMCC bought assets, IP and engineers concerning the PowerPC 400 microprocessors from IBM for $227 million and they now market the processors under their own name. The deal also included access to IBM's SoC design methodology and advanced CMOS process technology.

In 2009, AppliedMicro changed their branding from AMCC to AppliedMicro, but still retain the name "Applied Micro Circuits Corporation" officially.

In 2011, AppliedMicro became the first company to implement the ARMv8-A architecture with its X-Gene Platform. In November 2012 at ARM TechCon, AppliedMicro demonstrated advanced web search capabilities and the ability to handle big data workloads in an Apache Hadoop software environment with the X-Gene Platform using FPGA emulation. A silicon implementation of X-Gene was first exhibited publicly in June 2013.

In April 2016, information about the forthcoming X-Gene 3 server chips was made available. The release schedule is for the second half of 2017. The company projected an improved performance, over the X-Gene 2, that with allow it to better compete with servers using the x86-64 architecture.

In November 2016, Macom announced that they would purchase AppliedMicro.

AppliedMicro has a sponsor level membership of Power.org and is one of the original members. AppliedMicro is also executive member (Chairman position) of the Ethernet Alliance. AppliedMicro is also a member of the Open Compute Project.

The Processor Products group designs and markets embedded microcontrollers as well as server processor, packet and storage processors. It includes the network processors of former MMC Networks (acquired October 2000) with IBM PowerPC 4xx series microcontrollers (acquired April 2004).

Since purchasing the IBM PowerPC 400 family (under the 405 and 440 series product names), AppliedMicro has developed the 460 series with 440 CPU, and a multicore Power architecture devices.

In January 2008, the AppliedMicro PowerPC 405EX was awarded PRODUCT OF THE YEAR 2007, by Electronic Product Magazine.

In October 2011, AppliedMicro announced its X-Gene Platform, an ARM 64-bit solution aimed at cloud and enterprise servers.

The Connectivity Products group of AppliedMicro designs, manufacturers and markets physical layer devices, framers/mappers and switch fabric devices.

Throughout the years, AppliedMicro has acquired smaller companies to enter new markets.

In 2005, the company paid $60 million to settle a class-action lawsuit on behalf of investors against the company and certain of its current and former officers and directors. The suit had charged the company with issuing a series of materially false and misleading statements concerning the company's operations and prospects for Q4 2001 and beyond. Under the terms of the settlement, the company and defendants denied any wrongdoing. About half of the amount of the settlement was covered by insurance.